General Overview
Itraconazole is a broad-spectrum antifungal. It requires an acidic environment in the stomach for optimal absorption. It carries a warning for congestive heart failure.
Medicine Information
Itraconazole
Itraconazole
Prescription required
Antifungal
Medicine Safety Disclaimer
This information is for educational purposes only and should not be used for self-diagnosis or self-treatment. Do not start, stop, or change any medicine without consulting a qualified doctor or pharmacist. In case of overdose, severe allergic reaction, breathing difficulty, swelling of the face/lips, unconsciousness, or severe side effects, seek emergency medical help immediately.
Composition
Itraconazole IP
Strength
100 mg / 200 mg
Medicine Type
Capsule
Brand Names
Candiforce
Itraspor
Sporanox
Itaspor
Reported Uses
Used for treatment of dermatophytoses (ringworm, athlete's foot], vulvovaginal candidiasis, systemic mycoses, and fungal nail infections.
General Characteristics
Highly effective against a wide range of fungi. Penetrates and persists in skin and nails, providing long-term healing.
General Mechanism of Action
Inhibits fungal cytochrome P450-dependent synthesis of ergosterol, a vital component of fungal cell membranes.
Storage Guidelines
Store below 25°C in a dry place. Protect from light.
General Educational Notes
Always complete the full prescribed course. Taking it with an acidic beverage like cola can improve absorption if you have low stomach acid.
Frequently Asked Questions
Why must Candiforce be taken after food?
Itraconazole requires a highly acidic environment in the stomach to dissolve and be absorbed. Eating food stimulates stomach acid production, ensuring the drug is properly absorbed.
Can I take Itraconazole with antacids?
No. Antacids, H2 blockers, and PPIs reduce stomach acidity, which prevents Itraconazole from absorbing. Avoid taking antacids within 2 hours of this medicine.