General Overview
Sildenafil works by relaxing the blood vessels in the penis, allowing increased blood flow when sexually stimulated. It also dilates blood vessels in the lungs to reduce pulmonary blood pressure.
Medicine Information
Sildenafil
Sildenafil Citrate
Prescription required
Erectile Dysfunction / Pulmonary Hypertension
Medicine Safety Disclaimer
This information is for educational purposes only and should not be used for self-diagnosis or self-treatment. Do not start, stop, or change any medicine without consulting a qualified doctor or pharmacist. In case of overdose, severe allergic reaction, breathing difficulty, swelling of the face/lips, unconsciousness, or severe side effects, seek emergency medical help immediately.
Composition
Sildenafil Citrate IP
Strength
25 mg / 50 mg / 100 mg
Medicine Type
Tablet
Brand Names
Manforce
Vigore
Suhagra
Penegra
Reported Uses
Used for erectile dysfunction (ED) and to improve exercise capacity in patients with pulmonary arterial hypertension (PAH).
General Characteristics
Enables erectile function during sexual stimulation, and improves breathing and exercise tolerance in pulmonary hypertension patients.
General Mechanism of Action
Inhibits PDE5, which increases cyclic GMP levels in smooth muscle cells, leading to nitric oxide-mediated vasodilation of the corpus cavernosum and pulmonary vasculature.
Storage Guidelines
Store below 30°C in a dry place. Keep out of reach of children.
General Educational Notes
Seek medical help immediately if you experience an erection that lasts for more than 4 hours, as delayed treatment can cause permanent damage.
Frequently Asked Questions
Can I take Sildenafil with heart medicines?
You must NEVER take Sildenafil if you are taking nitrates (like nitroglycerin) for chest pain, as the combination can drop blood pressure to dangerous levels.
Does Sildenafil work without sexual stimulation?
No, Sildenafil requires sexual stimulation to work. It helps increase blood flow, but does not increase desire on its own.