General Overview
Glimepiride is a medium-to-long acting sulfonylurea. It works by increasing the amount of insulin released from the pancreas. It should always be combined with diet and exercise.
Medicine Information
Glimepiride
Glimepiride
Prescription required
Diabetes
Medicine Safety Disclaimer
This information is for educational purposes only and should not be used for self-diagnosis or self-treatment. Do not start, stop, or change any medicine without consulting a qualified doctor or pharmacist. In case of overdose, severe allergic reaction, breathing difficulty, swelling of the face/lips, unconsciousness, or severe side effects, seek emergency medical help immediately.
Composition
Glimepiride IP
Strength
1 mg / 2 mg / 3 mg / 4 mg
Medicine Type
Tablet
Brand Names
Amaryl
Glimy
GP
Reported Uses
Used to manage type 2 diabetes mellitus as an adjunct to diet and exercise.
General Characteristics
Effectively lowers HbA1c and daily blood glucose levels in patients with type 2 diabetes.
General Mechanism of Action
Stimulates insulin release from functioning pancreatic beta cells by binding to and blocking ATP-sensitive potassium channels in cell membranes.
Storage Guidelines
Store below 25°C in a dry place. Keep out of reach of children.
General Educational Notes
Educate family members on how to recognize signs of low blood sugar and how to administer glucagon or oral sugar in an emergency.
Frequently Asked Questions
What is the main side effect of Glimepiride?
The main and most common side effect is hypoglycemia (low blood sugar], which can occur if you skip meals or exercise excessively.
Can Glimepiride be used in Type 1 Diabetes?
No, Glimepiride only works when the pancreas is capable of producing insulin. Type 1 diabetics require insulin therapy.